A ROLE FOR METHYLATED BASES IN THE AMINO ACID ACCEPTOR FUNCTION OF SOLUBLE RIBONUCLEIC ACID
نویسندگان
چکیده
منابع مشابه
Species Specificity of Amino Acid Acceptor Ribonucleic Acid and Aminoacyl Soluble Ribonucleic Acid Synthetases.
Several investigators have reported that the activation of amino acids for protein synthesis, i.e. the incorporation of amino acids into soluble ribonucleic acids, is dependent upon the source of both the aminoacyl S-RNA’ synthetases and the S-RNA itself. For example, Rendi and Ochoa (1) reported that aminoacyl S-RNA synthetases from Escherichia coli could not incorporate leucine into yeast or ...
متن کاملOccurrence of Methylated Purine Bases in Yeast Ribonucleic Acid*
A number of methylated purine bases have recently been reported to occur in small quantities in the urine of normal human subjects. These include 1-methylguanine, iV*-methylguanine (6-hydroxy-2-methylaminopurine) ,I 1-methylhypoxanthine, and 8-hydroxy-7-methylguanine (1) in addition to 7-methylguanine, previously known as a urinary constituent (2). These compounds were found to be metabolites o...
متن کاملOccurrence of methylated purine bases in yeast ribonucleic acid.
A number of methylated purine bases have recently been reported to occur in small quantities in the urine of normal human subjects. These include 1-methylguanine, iV*-methylguanine (6-hydroxy-2-methylaminopurine) ,I 1-methylhypoxanthine, and 8-hydroxy-7-methylguanine (1) in addition to 7-methylguanine, previously known as a urinary constituent (2). These compounds were found to be metabolites o...
متن کاملThe Involvement of Soluble Ribonucleic Acid in Amino Acid Incorporation by a Maize System.
Much evidence, accumulated within the last 7 years, implicates soluble ribonucleic acid as a natural acceptor of activated amino acids and as an intermediate in the incorporation of amino acids into microsomal protein (l-3). Hoagland et al. (4) have delineated the essential features of the involvement of sRNAl in the cell-free amino acid-incorporating system from rat liver in terms of the curre...
متن کاملEORMllTION OF THE 3’-HY DROXYL TERMlNAL TltINUCLEOTIDE SEQUENCE OF AMINO ACID-ACCEPTOR RIBONUCLEIC ACID
The previous papers (1-3) and reports from numerous laboratories (4-9) have demonstrated the enzymic synthesis of amino acyl ribonucleic acid derivatives. Studies by Zachau et al. (IO), IIecht et al. (ll), and ourselves (3) have established that each amino acid is linked to a specific polynucleotide chain through an ester linkage with either the 2’or 3’-hydrosyl group of the terminal nucleotide...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1964
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.52.5.1233